Chronic kidney disease (CKD) affects 13.4% of the population, leading to a one-third increase in mortality rates over the past decade. In the end stage of CKD, one-third of all deaths are sudden deaths due to cardiac arrhythmias which are often linked to electrolyte imbalance. The end-stage CKD is treated with thrice-weekly hemodialysis, thus the time interval between the procedures increases 1.5 times during the weekend. Since about half of life-threatening conditions occur on the last day of the long interval, patient monitoring between the hemodialysis procedures is of special importance to prevent the hazardous outcome.
Through a detailed analysis of multimodal (biooptical, biopotential, biomechanical) biosignals, acquired using a wearable device, the KidneyLife tool provides a quantitative assessment of a CKD patient’s life-threatening conditions, i.e., electrolyte fluctuations and deadly arrhythmias. Relying on the analysis report, also including supplementary parameters, such as continuous blood pressure and pulse arrival time trends, the physician is given a better understanding of disease progression and the risk of life-threatening conditions of an individual patient.
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